Issue 30, 2005
From the journal:

Chemical Communications

High-density doxorubicin-conjugated polymeric nanoparticlesvia ring-opening metathesis polymerization†

Paul A. Bertin,a   DeeDee Smitha  and  SonBinh T. Nguyen*a  

* Corresponding authors

a Department of Chemistry and Center for Nanofabrication and Molecular Self-Assembly, Northwestern University, 2145 Sheridan Rd., Evanston, IL, USA
E-mail: stn@northwestern.edu

Abstract

High-density doxorubicin-conjugated polymeric nanoparticles are prepared via ring-opening metathesis polymerization and sustained release of nearly 50% of the anticancer agent is observed after 24 h in mildly acidic aqueous solution.

Graphical abstract: High-density doxorubicin-conjugated polymeric nanoparticles via ring-opening metathesis polymerization

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Article information

DOI
https://doi.org/10.1039/B504643B
Article type
Communication
Submitted
02 Apr 2005
Accepted
25 May 2005
First published
04 Jul 2005

Chem. Commun., 2005, 3793-3795

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High-density doxorubicin-conjugated polymeric nanoparticles via ring-opening metathesis polymerization

P. A. Bertin, D. Smith and S. T. Nguyen, Chem. Commun., 2005, 3793 DOI: 10.1039/B504643B

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