Issue 3, 2005
From the journal:

Chemical Communications

Polycationic dendrimers interact with RNA molecules: polyamine dendrimers inhibit the catalytic activity of Candida ribozymes†

Jiangyu Wu,a   Jiehua Zhou,a   Fanqi Qu,a   Penghui Bao,b   Yi Zhangb  and  Ling Peng*ac  

* Corresponding authors

a College of Chemistry and Molecular Sciences, Wuhan University, Wuhan 430072, China

b College of Life Sciences, Wuhan University, Wuhan 430072, China

c AFMB CNRS UMR 6098, 163, avenue de Luminy, Marseille, France
E-mail: ling@afmb.cnrs-mrs.fr
Fax: 33 4 9182 9491
Tel: 33 4 9182 9490

Abstract

Various polyamine dendrimers with a triethanolamine core inhibit the activity of the Candida ribozyme by forming RNA–dendrimer complexes via electrostatic interactions.

Graphical abstract: Polycationic dendrimers interact with RNA molecules: polyamine dendrimers inhibit the catalytic activity of Candida ribozymes

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Article information

DOI
https://doi.org/10.1039/B414241A
Article type
Communication
Submitted
17 Sep 2004
Accepted
26 Oct 2004
First published
09 Dec 2004

Chem. Commun., 2005, 313-315

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Polycationic dendrimers interact with RNA molecules: polyamine dendrimers inhibit the catalytic activity of Candida ribozymes

J. Wu, J. Zhou, F. Qu, P. Bao, Y. Zhang and L. Peng, Chem. Commun., 2005, 313 DOI: 10.1039/B414241A

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