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Issue 16, 2005
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Synthesis and stability of exocyclic triazine nucleosides

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Abstract

Synthesis and stability studies of exocyclic amino triazine nucleosides were performed. Stability of the nucleosides was found to be dependent on triazine ring electron density, solvent, and pH. The nucleosides were found to be more stable when the triazine ring was electron deficient, in high pH aqueous solutions and in aprotic solvents.

Graphical abstract: Synthesis and stability of exocyclic triazine nucleosides

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Publication details

The article was received on 14 Mar 2005, accepted on 18 May 2005 and first published on 19 Jul 2005


Article type: Paper
DOI: 10.1039/B503757C
Org. Biomol. Chem., 2005,3, 2946-2952

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    Synthesis and stability of exocyclic triazine nucleosides

    M. Hysell, J. S. Siegel and Y. Tor, Org. Biomol. Chem., 2005, 3, 2946
    DOI: 10.1039/B503757C

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