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Issue 2, 2005
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Disulfiram, an old drug with new potential therapeutic uses for human cancers and fungal infections

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Abstract

Disulfiram, a drug used to treat alcoholism, has recently been indicated to play a primary as well as an adjuvant role in the treatment of many cancers and in the reversal of fungal drug-resistance. This review discusses the molecular mechanism of action of disulfiram and its potential use in the treatment of human cancers and fungal infections.

Graphical abstract: Disulfiram, an old drug with new potential therapeutic uses for human cancers and fungal infections

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Publication details

The article was received on 30 Mar 2005, accepted on 16 May 2005 and first published on 26 May 2005


Article type: Review Article
DOI: 10.1039/B504392A
Mol. BioSyst., 2005,1, 127-134

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    Disulfiram, an old drug with new potential therapeutic uses for human cancers and fungal infections

    Z. E. Sauna, S. Shukla and S. V. Ambudkar, Mol. BioSyst., 2005, 1, 127
    DOI: 10.1039/B504392A

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