Issue 39, 2005
From the journal:

Chemical Communications

Accelerating chemical replication steps of RNA involving activated ribonucleotides and downstream-binding elements†

Stephanie R. Vogel,a   Christopher Decka  and  Clemens Richert*a  

* Corresponding authors

a Institute for Organic Chemistry, University of Karlsruhe (TH), 76131 Karlsruhe, Germany
E-mail: cr@rrg.uka.de
Fax: +49-721 608 4825
Tel: +49-721 608 2860

Abstract

Template-directed single nucleotide extension of an RNA primer with oxyazabenzotriazolides of ribonucleotides is shown to be fast and sequence-selective; downstream-binding RNA strands contribute to the acceleration of the reaction.

Graphical abstract: Accelerating chemical replication steps of RNA involving activated ribonucleotides and downstream-binding elements

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Article information

DOI
https://doi.org/10.1039/B510775J
Article type
Communication
Submitted
28 Jul 2005
Accepted
25 Aug 2005
First published
12 Sep 2005

Chem. Commun., 2005, 4922-4924

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Accelerating chemical replication steps of RNA involving activated ribonucleotides and downstream-binding elements

S. R. Vogel, C. Deck and C. Richert, Chem. Commun., 2005, 4922 DOI: 10.1039/B510775J

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