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Issue 42, 2005
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PNA forms an i-motif

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Abstract

A C-rich PNA hexanucleotide, p(C5T), has been shown to form an i-motif by nanoelectrospray ionization mass spectrometry coupled with H/D exchange, to have thermal stability comparable with its DNA analogue, but to exist over a much narrower pH range.

Graphical abstract: PNA forms an i-motif

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Article information


Submitted
22 Jul 2005
Accepted
23 Aug 2005
First published
23 Sep 2005

Chem. Commun., 2005, 5278-5280
Article type
Communication

PNA forms an i-motif

Y. Krishnan-Ghosh, E. Stephens and S. Balasubramanian, Chem. Commun., 2005, 5278
DOI: 10.1039/B510405J

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