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Low polydispersity poly(N-isopropylacrylamide) with a biotin end-group was obtained in one step from a biotinylated initiator for atom transfer radical polymerization and interacted with streptavidin to generate the thermosensitive polymerprotein conjugate.

Graphical abstract: One-step synthesis of low polydispersity, biotinylated poly(N-isopropylacrylamide) by ATRP

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