Issue 8, 2005

Room temperature palladium catalysed coupling of acyl chlorides with terminal alkynes

Abstract

Conditions are reported for the facile, high-yielding coupling of acyl chlorides with terminal alkynes in a reaction involving palladium and copper iodide; the reaction is tolerant of a wide variety of acyl chlorides and terminal alkynes and provides a convenient one-pot route to acetylenic ketones.

Graphical abstract: Room temperature palladium catalysed coupling of acyl chlorides with terminal alkynes

Supplementary files

Article information

Article type
Communication
Submitted
27 Sep 2004
Accepted
29 Oct 2004
First published
10 Jan 2005

Chem. Commun., 2005, 1037-1039

Room temperature palladium catalysed coupling of acyl chlorides with terminal alkynes

R. J. Cox, D. J. Ritson, T. A. Dane, J. Berge, J. P. H. Charmant and A. Kantacha, Chem. Commun., 2005, 1037 DOI: 10.1039/B414826F

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