Issue 1, 2005
From the journal:

Chemical Communications

Engineering stereocontrol into an aldolase-catalysed reaction†

Henry J. Lamble,a   Michael J. Danson,a   David W. Hougha  and  Steven D. Bull*b  

* Corresponding authors

a Centre for Extremophile Research, Department of Biology and Biochemistry, University of Bath, Bath, UK

b Department of Chemistry, University of Bath, Bath, UK
E-mail: S.D.Bull@bath.ac.uk
Fax: +44 (0)1225 386231
Tel: +44 (0)1225 383551

Abstract

A novel thermostable aldolase has been developed for synthetic application, and substrate engineering has been used to induce stereocontrol into aldol reactions of this naturally-promiscuous enzyme.

Graphical abstract: Engineering stereocontrol into an aldolase-catalysed reaction

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Article information

DOI
https://doi.org/10.1039/B413255F
Article type
Communication
Submitted
31 Aug 2004
Accepted
12 Oct 2004
First published
23 Nov 2004

Chem. Commun., 2005, 124-126

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Engineering stereocontrol into an aldolase-catalysed reaction

H. J. Lamble, M. J. Danson, D. W. Hough and S. D. Bull, Chem. Commun., 2005, 124 DOI: 10.1039/B413255F

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