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Issue 36, 2005
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Crystal engineering of pharmaceutical co-crystals from polymorphic active pharmaceutical ingredients

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Abstract

The carboxylic acidprimary amide supramolecular heterosynthon is exploited for the generation of pharmaceutical co-crystals that contain two active pharmaceutical ingredients that are polymorphic in their pure forms.

Graphical abstract: Crystal engineering of pharmaceutical co-crystals from polymorphic active pharmaceutical ingredients

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Supplementary files

Article information


Submitted
25 Jan 2005
Accepted
18 Jul 2005
First published
15 Aug 2005

Chem. Commun., 2005, 4601-4603
Article type
Communication

Crystal engineering of pharmaceutical co-crystals from polymorphic active pharmaceutical ingredients

P. Vishweshwar, J. A. McMahon, M. L. Peterson, M. B. Hickey, T. R. Shattock and M. J. Zaworotko, Chem. Commun., 2005, 4601 DOI: 10.1039/B501304F

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