Prodrugs of HIV protease inhibitors—saquinavir, indinavir and nelfinavir—derived from diglycerides or amino acids: synthesis, stability and anti-HIV activity†
Abstract
With the aim of improving the pharmacological properties of current
* Corresponding authors
a
Laboratoire de Chimie Bioorganique, UMR 6001 CNRS, Université de Nice Sophia-Antipolis, Parc Valrose, 06108 Nice Cédex 2, France
E-mail:
vierling@unice.fr
Fax: (33) (0)4 92 07 61 51
Tel: (33) (0)4 92 07 61 43
b INSERM U74, Institut de Virologie, 3 rue Koeberlé, 67000 Strasbourg, France
With the aim of improving the pharmacological properties of current
B. Gaucher, M. Rouquayrol, D. Roche, J. Greiner, A. Aubertin and P. Vierling, Org. Biomol. Chem., 2004, 2, 345 DOI: 10.1039/B313119J
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