Electrophilicity parameters for σ-complexation by uncharged electron-deficient aromatic and heteroaromatic structures
Abstract
Using appropriate sets of reference nucleophiles, the reactivity of neutral electrophiles of widely different reactivity and structure has been ranked on the comprehensive electrophilicity scale of Mayr (Acc. Chem. Res., 2003, 36, 66), holding promise of a general rationalization of σ-complexation processes and related SNAr substitutions.