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Issue 13, 2004
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Zinc–proline catalyzed pathway for the formation of sugars

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Abstract

Zn–proline catalyzes the aldolisation of unprotected glycolaldehyde in water to give tetroses and hexoses; threose (33% of the product mixture) was formed with 10% enantiomeric excess of the D-isomer.

Graphical abstract: Zinc–proline catalyzed pathway for the formation of sugars

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Article information


Submitted
25 Mar 2004
Accepted
07 May 2004
First published
27 May 2004

Chem. Commun., 2004, 1540-1541
Article type
Communication

Zinc–proline catalyzed pathway for the formation of sugars

J. Kofoed, M. Machuqueiro, J. Reymond and T. Darbre, Chem. Commun., 2004, 1540
DOI: 10.1039/B404465G

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