Issue 5, 2004
From the journal:

Chemical Communications

A ratiometric fluorescent probe for imaging hydroxyl radicals in living cells†

Nobuaki Soh,a   Koji Makihara,a   Emino Sakodaa  and  Toshihiko Imato*a  

* Corresponding authors

a Department of Applied Chemistry, Graduate School of Engineering, Kyushu University, 6-10-1, Hakozaki, Higashi-ku, Fukuoka 812-8581, Japan
E-mail: imato@cstf.kyushu-u.ac.jp

Abstract

A novel fluorescent probe, the detection mechanism of which is based on the ‘on-off’ switching of a FRET triggered by the ˙OH-induced cleavage of a DNA strand, has been developed for the ratiometric imaging of ˙OH.

Graphical abstract: A ratiometric fluorescent probe for imaging hydroxyl radicals in living cells

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Article information

DOI
https://doi.org/10.1039/B314204C
Article type
Communication
Submitted
07 Nov 2003
Accepted
22 Dec 2003
First published
02 Feb 2004

Chem. Commun., 2004, 496-497

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A ratiometric fluorescent probe for imaging hydroxyl radicals in living cells

N. Soh, K. Makihara, E. Sakoda and T. Imato, Chem. Commun., 2004, 496 DOI: 10.1039/B314204C

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