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Issue 3, 2004
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Anti-viral cyclam macrocycles : rapid zinc uptake at physiological pH

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Abstract

NMR and UV-vis spectroscopic studies show that Zn(II) binds to cyclam rapidly at micromolar concentrations, an observation relevant to the anti-viral activity and co-receptor binding of anti-HIV cyclams.

Graphical abstract: Anti-viral cyclam macrocycles : rapid zinc uptake at physiological pH

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Publication details

The article was received on 14 Oct 2003, accepted on 04 Dec 2003 and first published on 06 Jan 2004


Article type: Communication
DOI: 10.1039/B312752B
Chem. Commun., 2004, 306-307

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    Anti-viral cyclam macrocycles : rapid zinc uptake at physiological pH

    S. J. Paisey and P. J. Sadler, Chem. Commun., 2004, 306
    DOI: 10.1039/B312752B

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