Issue 20, 2003
From the journal:

Chemical Communications

Novel poly(amino ester)s obtained from Michael addition polymerizations of trifunctional amine monomers with diacrylates: safe and efficient DNA carriers†

Ye Liu,*a   Decheng Wu,ab   Yuexia Ma,a   Guping Tang,a   Shu Wang,a   Chaobin He,a   Taishung Chungc  and  Suathong Gohb  

* Corresponding authors

a Institute of Materials Research and Engineering, 3 Research Link, Singapore 117602
E-mail: ye-liu@imre.a-star.edu.sg.
Fax: 65-6872 7528
Tel: 65-6874 8105

b Department of Chemistry, National University of Singapore, 3 Science Drive 3, Singapore 117543

c Department of Chemical and Environmental Engineering, National University of Singapore, Singapore 119260

Abstract

Novel biodegradable poly(amino ester)s containing secondary and tertiary amines in the backbones were obtained from the Michael addition polymerizations of trifunctional amine monomers with diacrylates, and showed high transfection efficiency for the delivery of DNA comparable to those of polyethylenimine (PEI) and low cytotoxicity.

Graphical abstract: Novel poly(amino ester)s obtained from Michael addition polymerizations of trifunctional amine monomers with diacrylates: safe and efficient DNA carriers

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Article information

DOI
https://doi.org/10.1039/B309487A
Article type
Communication
Submitted
08 Aug 2003
Accepted
28 Aug 2003
First published
16 Sep 2003

Chem. Commun., 2003, 2630-2631

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Novel poly(amino ester)s obtained from Michael addition polymerizations of trifunctional amine monomers with diacrylates: safe and efficient DNA carriers

Y. Liu, D. Wu, Y. Ma, G. Tang, S. Wang, C. He, T. Chung and S. Goh, Chem. Commun., 2003, 2630 DOI: 10.1039/B309487A

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