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Issue 18, 2003
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The first Pummerer cyclisations on solid phase. Convenient construction of oxindoles enabled by a sulfur-link to resin

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Abstract

α-Sulfanyl N-aryl acetamides, attached to resin via the sulfur atom, undergo efficient Pummerer cyclisation upon activation of the sulfur link, to give oxindoles; heterocyclic products can be cleaved from the resin in a traceless manner using samarium(II) iodide.

Graphical abstract: The first Pummerer cyclisations on solid phase. Convenient construction of oxindoles enabled by a sulfur-link to resin

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Publication details

The article was received on 03 Jul 2003, accepted on 05 Aug 2003 and first published on 19 Aug 2003


Article type: Communication
DOI: 10.1039/B307586A
Citation: Chem. Commun., 2003,0, 2380-2381
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    The first Pummerer cyclisations on solid phase. Convenient construction of oxindoles enabled by a sulfur-link to resin

    L. A. McAllister, S. Brand, R. de Gentile and D. J. Procter, Chem. Commun., 2003, 0, 2380
    DOI: 10.1039/B307586A

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