Jump to main content
Jump to site search
PLANNED MAINTENANCE Close the message box

Scheduled maintenance work on Wednesday 27th March 2019 from 11:00 AM to 1:00 PM (GMT).

During this time our website performance may be temporarily affected. We apologise for any inconvenience this might cause and thank you for your patience.


Issue 12, 2003
Previous Article Next Article

A highly efficient catalytic system for cross-coupling of aryl chlorides and bromides with malononitrile anion by palladium carbene complexes

Author affiliations

Abstract

Six imidazolium chlorides (1–6) as precursors of 1,3-diaryl substituted N-heterocyclic carbene ligands were synthesized and evaluated in palladium-catalyzed cross-coupling reactions of aryl chlorides and bromides with malononitrile in the presence of NaH. Among them, 1,3-bis(2,4,6-triethylphenyl)imidazolium chloride (5) and 1,3-bis(2,4,6-triisopropylphenyl)imidazolium chloride (6) are novel. The catalytic system combining Pd(0) with imidazolium salts 4, 5 and 6 with bulky aryl groups in pyridine is found to be superior over others and afforded α-arylmalononitriles in high yields when employing a wide variety of substrates.

Graphical abstract: A highly efficient catalytic system for cross-coupling of aryl chlorides and bromides with malononitrile anion by palladium carbene complexes

Back to tab navigation

Supplementary files

Publication details

The article was received on 12 Mar 2003, accepted on 07 May 2003 and first published on 20 May 2003


Article type: Communication
DOI: 10.1039/B302890A
Citation: Chem. Commun., 2003,0, 1444-1445

  •   Request permissions

    A highly efficient catalytic system for cross-coupling of aryl chlorides and bromides with malononitrile anion by palladium carbene complexes

    C. Gao, X. Tao, Y. Qian and J. Huang, Chem. Commun., 2003, 0, 1444
    DOI: 10.1039/B302890A

Search articles by author

Spotlight

Advertisements