The role of the counteranion in the cation-π interaction
Abstract
Chemical double mutant cycles have been used to quantify cation-π interactions in chloroform as a function of the nature of the counteranion. The cation-π interaction is −2.5 ± 0.4 kJ mol−1 and independent of the anion, even though the overall stability of the complexes varies by an order of magnitude due to competition of the anion for alternative binding sites.