Jump to main content
Jump to site search

Issue 2, 2003
Previous Article Next Article

Recent advances in antimicrobial nucleoside antibiotics targeting cell wall biosynthesis

Author affiliations

Abstract

Covering: Until September 2002

The biosynthesis of peptidoglycan is essential for all bacteria and has no counterpart in eukaryotic cells. It is one of the prime targets for antibiotic chemotherapy, especially phospho-MurNAc-pentapeptide translocase (translocase I) is a fascinating target in which there is no commercial antibiotic. In this review we will describe three nucleoside translocase I inhibitors, mureidomycin, tunicamycin and liposidomycin.

Back to tab navigation

Article information


Submitted
19 Nov 2002
First published
03 Mar 2003

Nat. Prod. Rep., 2003,20, 252-273
Article type
Review Article

Recent advances in antimicrobial nucleoside antibiotics targeting cell wall biosynthesis

K. Kimura and T. D. H. Bugg, Nat. Prod. Rep., 2003, 20, 252
DOI: 10.1039/B202149H

Social activity

Search articles by author

Spotlight

Advertisements