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Issue 2, 2003
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In situ fabricated porous filters for microsystems

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Abstract

Porous filters were fabricated inside a microchannel using emulsion photo-polymerization. The porosity of the filter is dependent on the composition of the pre-polymer mixture. The morphology and flow resistance of four filters with varying water and cross-linker concentrations was studied. The porous filter was used to separate samples, such as whole blood to cell/serum components, based on size. The efficiency of cell/serum separation by the porous filter was tested by performing a glucose-6-phosphate dehydrogenase assay and was found to be comparable to separation by centrifuge. The porous filter thus mimics the functionality of the centrifuge, with the added benefits of no power requirements and ability to handle small sample volumes.

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Publication details

The article was received on 14 Jan 2003, accepted on 08 Apr 2003 and first published on 30 Apr 2003


Article type: Paper
DOI: 10.1039/B300450C
Lab Chip, 2003,3, 62-66

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    In situ fabricated porous filters for microsystems

    J. Moorthy and D. J. Beebe, Lab Chip, 2003, 3, 62
    DOI: 10.1039/B300450C

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