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Issue 3, 2003
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Infrared-assisted eco-friendly selective synthesis of diindolylmethanes

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Abstract

An alternative and environmentally benign pathway for selective synthesis of aryl-3,3′-diindolylmethanes from indole and several aromatic aldehydes is described. The electrophilic aromatic substitution (EAS) reactions are achieved with good yield and short reaction time employing infrared irradiation as energy source and a bentonitic clay as catalyst and reaction medium, in solvent-free reaction conditions.

Graphical abstract: Infrared-assisted eco-friendly selective synthesis of diindolylmethanes

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Publication details

The article was received on 08 Nov 2002 and first published on 08 May 2003


Article type: Paper
DOI: 10.1039/B211011C
Green Chem., 2003,5, 337-339

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    Infrared-assisted eco-friendly selective synthesis of diindolylmethanes

    G. Penieres-Carrillo, J. G. García-Estrada, J. L. Gutiérrez-Ramírez and C. Alvarez-Toledano, Green Chem., 2003, 5, 337
    DOI: 10.1039/B211011C

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