Microwave-induced organometallic reactions in aqueous media. Use of Ga and Bi for the allylation of aromatic N-oxides and hydrazones

Abstract

Homoallylic hydroxylamines and homoallylic hydrazides were synthesised in excellent yields by the reaction of allylgallium or allylbismuth reagent, generated in situ in the presence of 0.1 equivalent of NH₄Cl–Bu₄NBr, with aldonitrones and hydrazones in aqueous media. The reaction rate can be increased dramatically under microwave activation.