Issue 20, 2002
From the journal:

Chemical Communications

A flexible strategy for the divergent modification of pleuromutilin

Eric Bacqué,a   François Pautratb  and  Samir Z. Zard*b  

* Corresponding authors

a Aventis, Centre de Recherche de Romainville, 102 Route de Noisy, Romainville, France

b Laboratoire de Synthèse Organique Associé au CNRS, Ecole Polytechnique, Palaiseau, France
E-mail: zard@poly.polytechnique.fr
Fax: +33 (0)169333851
Tel: +33 (0)169334872

Abstract

The complex antibacterial natural product, pleuromutilin, can be directly modified by the radical addition reaction of various xanthates to the unactivated terminal olefin present on C-12.

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Article information

DOI
https://doi.org/10.1039/B206568A
Article type
Communication
Submitted
08 Jul 2002
Accepted
12 Sep 2002
First published
23 Sep 2002

Chem. Commun., 2002, 2312-2313

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A flexible strategy for the divergent modification of pleuromutilin

E. Bacqué, F. Pautrat and S. Z. Zard, Chem. Commun., 2002, 2312 DOI: 10.1039/B206568A

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