Issue 20, 2002
From the journal:

Chemical Communications

Synthesis of long Poly(dA)·Poly(dT) DNA without structural defects using enzymatic reaction; Tailored ligated Poly(dA)·Poly(dT)†

Shin-ichi Tanaka,a   Shinsuke Fujiwara,b   Hiroyuki Tanaka,a   Masateru Taniguchi,a   Hitoshi Tabata,a   Kiichi Fukuic  and  Tomoji Kawai*a  

* Corresponding authors

a The Institute of Scientific and Industrial Research, Osaka University, 8-1 Mihogaoka, Ibaraki, Osaka 567-0047, Japan
E-mail: kawai@sanken.osaka-u.ac.jp
Fax: +81-6-6875-2440
Tel: +81-6-6879-8447

b Department of Life Science, School of Science and Technology, Kwansei Gakuin University, 2-1 Gakuen, Sanda, Japan
Fax: +81-795-65-9077
Tel: +81-795-65-7829

c Department of Biotechnology, Graduate School of Engineering, Osaka University, 2-1 Yamadaoka, Suita, Osaka 567-0871, Japan
Fax: +81-6-6879-7441
Tel: +81-6-6879-7440

Abstract

Poly(dA)·Poly(dT) molecules up to 1000 base pairs (bp) have been synthesized using enzymatic reaction, and characterization by STM observation shows that the DNA has no defects in the duplex structure.

Graphical abstract: Synthesis of long Poly(dA)·Poly(dT) DNA without structural defects using enzymatic reaction; Tailored ligated Poly(dA)·Poly(dT)

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Article information

DOI
https://doi.org/10.1039/B205821A
Article type
Communication
Submitted
17 Jun 2002
Accepted
29 Aug 2002
First published
16 Sep 2002

Chem. Commun., 2002, 2330-2331

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Synthesis of long Poly(dA)·Poly(dT) DNA without structural defects using enzymatic reaction; Tailored ligated Poly(dA)·Poly(dT)

S. Tanaka, S. Fujiwara, H. Tanaka, M. Taniguchi, H. Tabata, K. Fukui and T. Kawai, Chem. Commun., 2002, 2330 DOI: 10.1039/B205821A

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