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Issue 17, 2002
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Synthesis of the bicyclic dienone core of the antitumor agent ottelione B

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Abstract

The intramolecular Diels–Alder adduct 12 was converted via dimesylate 20 into dienone 7, which represents the unusual, and apparently quite stable, core of the antitumor agent ottelione B (1).

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Article information


Submitted
05 Jun 2002
Accepted
28 Jun 2002
First published
31 Jul 2002

Chem. Commun., 2002, 1940-1941
Article type
Communication

Synthesis of the bicyclic dienone core of the antitumor agent ottelione B

D. L. J. Clive and S. P. Fletcher, Chem. Commun., 2002, 1940
DOI: 10.1039/B205753K

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