Issue 17, 2002
From the journal:

Chemical Communications

Synthesis of BF2 chelates of tetraarylazadipyrromethenes and evidence for their photodynamic therapeutic behaviour

John Killoran,a   Lorcan Allen,b   John F. Gallagher,c   William M. Gallagherb  and  Donal F. O′Shea*a  

* Corresponding authors

a Centre for Synthesis and Chemical Biology, Conway Institute, Department of Chemistry, University College Dublin, Belfield, Dublin 4, Ireland
E-mail: donal.f.oshea@ucd.ie

b Department of Pharmacology, Conway Institute, University College Dublin, Belfield, Dublin 4, Ireland

c School of Chemical Sciences, Dublin City University, Dublin 9, Ireland

Abstract

The synthesis, spectroscopic characteristics and in vitro cellular uptake properties of a new class of therapeutic window photosensitiser, namely the BF2 chelates of 3,5-diaryl-1H-pyrrol-2-yl-3,5-diarylpyrrol-2-ylidene amines (tetraarylazadipyrromethenes), are described with the aim of developing a novel class of photodynamic therapeutic agents.

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Article information

DOI
https://doi.org/10.1039/B204317C
Article type
Communication
Submitted
09 May 2002
Accepted
08 Jul 2002
First published
23 Jul 2002

Chem. Commun., 2002, 1862-1863

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Synthesis of BF2 chelates of tetraarylazadipyrromethenes and evidence for their photodynamic therapeutic behaviour

J. Killoran, L. Allen, J. F. Gallagher, W. M. Gallagher and D. F. O′Shea, Chem. Commun., 2002, 1862 DOI: 10.1039/B204317C

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