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Issue 6, 2002
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Reduction of α-aryloxy carbonyl compounds with samarium(II) iodide. A new traceless linker for the solid phase synthesis of carbonyl compounds

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Abstract

A new linker for the solid phase synthesis of functionalised carbonyl compounds which is cleaved under mild, neutral conditions using samarium(II) iodide has been developed; the manipulation of an immobilised γ-butyrolactone has been carried out to illustrate the utility of the linker.

Graphical abstract: Reduction of α-aryloxy carbonyl compounds with samarium(ii) iodide. A new traceless linker for the solid phase synthesis of carbonyl compounds

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Publication details

The article was received on 09 Jan 2002, accepted on 31 Jan 2002 and first published on 18 Feb 2002


Article type: Communication
DOI: 10.1039/B200365C
Citation: Chem. Commun., 2002,0, 584-585
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    Reduction of α-aryloxy carbonyl compounds with samarium(II) iodide. A new traceless linker for the solid phase synthesis of carbonyl compounds

    F. McKerlie, D. J. Procter and G. Wynne, Chem. Commun., 2002, 0, 584
    DOI: 10.1039/B200365C

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