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Issue 6, 2002
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Reduction of α-aryloxy carbonyl compounds with samarium(ii) iodide. A new traceless linker for the solid phase synthesis of carbonyl compounds

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Abstract

A new linker for the solid phase synthesis of functionalised carbonyl compounds which is cleaved under mild, neutral conditions using samarium(II) iodide has been developed; the manipulation of an immobilised γ-butyrolactone has been carried out to illustrate the utility of the linker.

Graphical abstract: Reduction of α-aryloxy carbonyl compounds with samarium(ii) iodide. A new traceless linker for the solid phase synthesis of carbonyl compounds

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Article information


Submitted
09 Jan 2002
Accepted
31 Jan 2002
First published
18 Feb 2002

Chem. Commun., 2002, 584-585
Article type
Communication

Reduction of α-aryloxy carbonyl compounds with samarium(II) iodide. A new traceless linker for the solid phase synthesis of carbonyl compounds

F. McKerlie, D. J. Procter and G. Wynne, Chem. Commun., 2002, 584
DOI: 10.1039/B200365C

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