Jump to main content
Jump to site search

Issue 12, 2002
Previous Article Next Article

5-Diisopropoxyphosphoryl-5-methyl-1-pyrroline N-oxide, DIPPMPO, a crystalline analog of the nitrone DEPMPO: synthesis and spin trapping properties

Author affiliations

Abstract

The nitrone DIPPMPO (5-diisopropoxyphosphoryl-5-methyl-1-pyrroline N-oxide) was synthesised, isolated as hygroscopic crystals and its X-ray geometry was determined. The purification of DIPPMPO was easy, compared with that of DEPMPO (5-diethoxyphosphoryl-5-methyl-1-pyrroline N-oxide) and its solutions in phosphate buffer were EPR silent. DIPPMPO exhibits all the advantages of DEPMPO for the spin-trapping of biological free radicals and thus DIPPMPO is a choice tool in this field.

Graphical abstract: 5-Diisopropoxyphosphoryl-5-methyl-1-pyrroline N-oxide, DIPPMPO, a crystalline analog of the nitrone DEPMPO: synthesis and spin trapping properties

Back to tab navigation

Supplementary files

Publication details

The article was received on 15 Jul 2002, accepted on 10 Oct 2002 and first published on 12 Nov 2002


Article type: Paper
DOI: 10.1039/B206909C
J. Chem. Soc., Perkin Trans. 2, 2002, 2110-2117

  •   Request permissions

    5-Diisopropoxyphosphoryl-5-methyl-1-pyrroline N-oxide, DIPPMPO, a crystalline analog of the nitrone DEPMPO: synthesis and spin trapping properties

    F. Chalier and P. Tordo, J. Chem. Soc., Perkin Trans. 2, 2002, 2110
    DOI: 10.1039/B206909C

Search articles by author

Spotlight

Advertisements