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Issue 2, 2002
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An evaporation-based microfluidic sample concentration method

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We present a method for sample concentration within microfluidic devices using evaporation-induced flow. Evaporation-induced flow is easy to incorporate into microfluidic designs and can be used to concentrate a wide variety of molecules. The practicality of this method was demonstrated with 0.2 μm fluorescent spheres and FITC-labeled BSA. Thirty two percent of the 0.6 μL fluorescent sphere suspension was concentrated into a well within a microfluidic device. In the same amount of time, 93% of the 0.6 μL FITC-labeled BSA solution was concentrated.

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Article information

11 Mar 2002
15 Apr 2002
First published
30 Apr 2002

Lab Chip, 2002,2, 57-61
Article type

An evaporation-based microfluidic sample concentration method

G. M. Walker and D. J. Beebe, Lab Chip, 2002, 2, 57
DOI: 10.1039/B202473J

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