Competing inter- and intramolecular hydrogen bonding: solvent-driven rotamerization in 3,4-(ethylenedioxy)-2-thienyldi(tert-alkyl)methanols
Abstract
3,4-(Ethylenedioxy)-2-thienyldi(tert-alkyl)methanols exist in two rotameric forms, the equilibrium constant for the anti⇌syn rotamerization depending on the ]) is close to unity in
H2). The temperature dependence of the rotamer ratio in strongly hydrogen-bonding