6-Substituted 2-azabicyclo[2.2.1]hept-5-enes by nitrogen-directed radical rearrangement: synthesis of an epibatidine analogue with high binding affinity at the nicotinic acetylcholine receptor†
Abstract
Base-induced isomerisation of
* Corresponding authors
a Dyson Perrins Laboratory, Department of Chemistry, University of Oxford, South Parks Road, Oxford, UK
b Syngenta, Jealott's Hill International Research Centre, Berkshire, UK
c Department of Pharmacology, University College London, Gower Street, London, UK
d Department of Biology and Biochemistry, University of Bath, Bath, UK
Base-induced isomerisation of
D. M. Hodgson, C. R. Maxwell, R. Wisedale, I. R. Matthews, K. J. Carpenter, A. H. Dickenson and S. Wonnacott, J. Chem. Soc., Perkin Trans. 1, 2001, 3150 DOI: 10.1039/B107414H
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