Polyhalogenated heterocyclic compounds. Part 47. Syntheses of multi-substituted pyridine derivatives from pentafluoropyridine

Richard D. Chambers; Philip R. Hoskin; Graham Sandford; Dmitrii S. Yufit; Judith A. K. Howard

doi:10.1039/B105950P

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Polyhalogenated heterocyclic compounds. Part 47.¹ Syntheses of multi-substituted pyridine derivatives from pentafluoropyridine

Richard D. Chambers,*^a Philip R. Hoskin,^a Graham Sandford,*^a Dmitrii S. Yufit^b and Judith A. K. Howard^b

Author affiliations

* Corresponding authors

^a Department of Chemistry, University of Durham, South Road, Durham, UK
E-mail: r.d.chambers@durham.ac.uk, graham.sandford@durham.ac.uk

^b Chemical Crystallography Unit, Department of Chemistry, University of Durham, South Road, Durham, UK

Abstract

A sequence of nucleophilic aromatic substitution and palladium catalysed coupling processes were used to transform pentafluoropyridine into various pyridine derivatives that bear five different functional groups.

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Supplementary files

Crystal structure data TXT (26K)

Article information

DOI: https://doi.org/10.1039/B105950P
Article type: Paper
Submitted: 04 Jul 2001
Accepted: 12 Sep 2001
First published: 09 Oct 2001

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J. Chem. Soc., Perkin Trans. 1, 2001, 2788-2795

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Polyhalogenated heterocyclic compounds. Part 47. Syntheses of multi-substituted pyridine derivatives from pentafluoropyridine

R. D. Chambers, P. R. Hoskin, G. Sandford, D. S. Yufit and J. A. K. Howard, J. Chem. Soc., Perkin Trans. 1, 2001, 2788 DOI: 10.1039/B105950P

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Journal of the Chemical Society, Perkin Transactions 1