Issue 15, 2001
From the journal:

Journal of the Chemical Society, Perkin Transactions 1

Bio-organic synthesis of a newly isolated peptide metastin, metastasis suppressor gene KiSS-1 processing product†

Osamu Nishimura,a   Masato Suenaga,a   Takao Yamada,a   Takashi Itoh,a   Nobuyuki Koyama,a   Mitsuhiro Wakimasu,a   Tetsuya Ohtaki,a   Chieko Kitadaa  and  Masahiko Fujinoa  

a Pharmaceutical Research Division, Takeda Chemical Industries, Ltd., Wadai-10, Tsukuba, Ibaraki 300 4293, Japan
E-mail: Kitada_Chieko@takeda.co.jp
Fax: 81-298-64-5000
Tel: 81-298-64-5004

Abstract

Metastin, a newly isolated peptide ligand of orphan receptor hOT7T175, was synthesized by a bio-organic technique combining recombinant DNA technology with a cysteine-specific cleavage reaction.

Graphical abstract: Bio-organic synthesis of a newly isolated peptide metastin, metastasis suppressor gene KiSS-1 processing product

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Article information

DOI
https://doi.org/10.1039/B104948H
Article type
Communication
Submitted
05 Jun 2001
Accepted
27 Jun 2001
First published
09 Jul 2001

J. Chem. Soc., Perkin Trans. 1, 2001, 1748-1750

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Bio-organic synthesis of a newly isolated peptide metastin, metastasis suppressor gene KiSS-1 processing product

O. Nishimura, M. Suenaga, T. Yamada, T. Itoh, N. Koyama, M. Wakimasu, T. Ohtaki, C. Kitada and M. Fujino, J. Chem. Soc., Perkin Trans. 1, 2001, 1748 DOI: 10.1039/B104948H

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