Spirostanic analogues of teasterone. Synthesis, characterisation and biological activity of laxogenin, (23S)-hydroxylaxogenin and 23-ketolaxogenin (23-oxolaxogenin)

Martín A. Iglesias-Arteaga; Roxana Pérez Gil; Carlos S. Pérez Martínez; Francisco Coll Manchado

doi:10.1039/B007656M

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Spirostanic analogues of teasterone. Synthesis, characterisation and biological activity of laxogenin, (23S)-hydroxylaxogenin and 23-ketolaxogenin (23-oxolaxogenin)

Martín A. Iglesias-Arteaga,*^a Roxana Pérez Gil,^a Carlos S. Pérez Martínez^a and Francisco Coll Manchado^a

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* Corresponding authors

^a Laboratorio de Productos Naturales, Facultad de Química, Universidad de La Habana, La Habana, Cuba
E-mail: iglesias@fq.uh.cu

Abstract

The synthesis and characterisation of the naturally occurring steroid sapogenin laxogenin 1 and its derivatives 23-ketolaxogenin 10 and (23S)-hydroxylaxogenin 13 are described. Compounds reported have shown plant-growth-stimulating activity in in vitro tests and in field trials.

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DOI: https://doi.org/10.1039/B007656M
Article type: Paper
Submitted: 20 Sep 2000
Accepted: 10 Nov 2000
First published: 16 Jan 2001

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J. Chem. Soc., Perkin Trans. 1, 2001, 261-266

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Spirostanic analogues of teasterone. Synthesis, characterisation and biological activity of laxogenin, (23S)-hydroxylaxogenin and 23-ketolaxogenin (23-oxolaxogenin)

M. A. Iglesias-Arteaga, R. Pérez Gil, C. S. Pérez Martínez and F. Coll Manchado, J. Chem. Soc., Perkin Trans. 1, 2001, 261 DOI: 10.1039/B007656M

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Journal of the Chemical Society, Perkin Transactions 1

Spirostanic analogues of teasterone. Synthesis, characterisation and biological activity of laxogenin, (23S)-hydroxylaxogenin and 23-ketolaxogenin (23-oxolaxogenin)

Abstract

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Spirostanic analogues of teasterone. Synthesis, characterisation and biological activity of laxogenin, (23S)-hydroxylaxogenin and 23-ketolaxogenin (23-oxolaxogenin)

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