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Issue 24, 2001
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Pseudoxazolones, a new class of inhibitors for cysteine proteinases: inhibition of hepatitis A virus and human rhinovirus 3C proteinases

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Abstract

Monophenyl and diphenyl pseudoxazolone derivatives of glycine and alanine were prepared and found to be time-dependent inhibitors of hepatitis A virus (HAV) 3C and human rhinovirus (HRV) 3C proteinases with IC50 values in the micromolar range.

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Article information


Submitted
09 Oct 2001
Accepted
14 Nov 2001
First published
06 Dec 2001

Chem. Commun., 2001, 2740-2741
Article type
Communication

Pseudoxazolones, a new class of inhibitors for cysteine proteinases: inhibition of hepatitis A virus and human rhinovirus 3C proteinases

Y. K. Ramtohul, N. I. Martin, L. Silkin, M. N. G. James and J. C. Vederas, Chem. Commun., 2001, 2740
DOI: 10.1039/B109095J

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