Zr(OtBu)4-catalysed synthesis of acetone aldol adducts and domino aldol-Tishchenko reactions with diacetone alcohol as enol equivalentDedicated to Professor David A. Evans on the occasion of his 60th birthday.
Abstract
Zr(OtBu)4 was found to be a potent catalyst for the synthesis of acetone aldol adducts with diacetone alcohol as enol equivalent and for domino aldol-Tishchenko reaction giving rise to 1,3-anti-diol monoesters with excellent diastereoselectivity.