5-Exo-dig, 5-exo-trig cascade radical cyclisation on sugar-furanose templates: entry to angularly fused oxa- and dioxa-triquinane skeletons

Abstract

Serial radical cyclisation on sugar-furanose templates to create angularly fused oxa- and dioxa-triquinane skeletons has been described, the salient feature of this approach being to incipiently generate a tertiary radical from cyclopropylmethyl bromide with simultaneous release of allyl group and to subsequently incorporate it in the triquinane system.