Design, machine synthesis, and NMR-solution structure of a β-heptapeptide forming a salt-bridge stabilised 314-helix in methanol and in waterElectronic supplementary information (ESI) available: NMR spectroscopy and conc. dependent CD-spectra of 1. See http://www.rsc.org/suppdata/cc/b1/b101085i/
Abstract
Salt-bridge formation may be used to stabilise the 314-helical conformation of β-peptides in aqueous solution, as shown by a 2D-NMR spectroscopic investigation.