β-Sultams—A novel class of serine protease inhibitors
Abstract
N-Benzoyl β-sultam is an irreversible inactivator of elastase by sulfonation of the active site serine.
* Corresponding authors
a Department of Chemical and Biological Sciences, University of Huddersfield, Queensgate, Huddersfield, UK
b Oxford Centre for Molecular Sciences and the Dyson Perrins Laboratory, South Parks Road, Oxford, UK
N-Benzoyl β-sultam is an irreversible inactivator of elastase by sulfonation of the active site serine.
β-Sultams—A novel class of serine protease inhibitors
M. Beardsell, P. S. Hinchliffe, J. M. Wood, R. C. Wilmouth, C. J. Schofield and M. I. Page, Chem. Commun., 2001, 497 DOI: 10.1039/B100294P
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