Issue 3, 2001
From the journal:

Chemical Communications

Synthesis and antibody binding properties of glycodendrimers bearing the tumor related T-antigen

Myung-Gi Baek,a   Kate Rittenhouse-Olsonb  and  René Roy*a  

* Corresponding authors

a Department of Chemistry, University of Ottawa, 10 Marie Curie, Ottawa, Ontario, Canada

b Department of Microbiology and Immunology, Roswell Park Division, State University of New York at Buffalo, Buffalo, NY 14214., USA.
E-mail: rroy@science.uottawa.ca
Fax: +1-613-562-5170
Tel: +1-613-562-5800 ext 6055

Abstract

Breast cancer marker T-antigen (Gal(β1-3)αGalNAc) was prepared as an allyl glycoside that was transformed into an active ester and coupled to a series of poly(amidoamine) dendrimers showing strong binding to mouse monoclonal IgG antibodies and serving as useful coating antigens in microtiter plates.

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Article information

DOI
https://doi.org/10.1039/B008664I
Article type
Communication
Submitted
23 Oct 2000
Accepted
08 Dec 2000
First published
23 Jan 2001

Chem. Commun., 2001, 257-258

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Synthesis and antibody binding properties of glycodendrimers bearing the tumor related T-antigen

M. Baek, K. Rittenhouse-Olson and R. Roy, Chem. Commun., 2001, 257 DOI: 10.1039/B008664I

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