The use of high resolution diffusion-ordered NMR spectroscopy (HR-DOSY) to detect association between a soluble polymer and different components of small libraries of soluble compounds is illustrated for libraries binding respectively to weakly acidic and weakly basic polymers.
A novel NMR method for screening soluble compound libraries
P. Hodge, P. Monvisade, G. A. Morris and I. Preece, Chem. Commun., 2001, 239 DOI: 10.1039/B008412N
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