A glucose biosensor based on electrodeposited biocomposites of gold nanoparticles and glucose oxidase enzyme

Abstract

Electrodeposition was used for the codeposition of glucose oxidase enzyme and a gold nanoparticle–silicate network onto an indium tin oxide (ITO) glass electrode. This co-entrapment of glucose oxidase enzyme in a gold nanoparticle–silicate network imparts biocatalytic activity to the film. The gold nanoparticles in the network catalyse the oxidation and reduction of H₂O₂, the by-product of the enzymatic reaction. The low operating potential of the sensor eliminates the interference from common interferents, such as acetaminophen, ascorbic acid, dopamine, etc.