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Issue 20, 2001
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Sequence fidelity of a template-directed PNA-ligation reactionPNA = peptide nucleic acid.12

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Abstract

The ligation method and an appended duplex-stabilizing dye affect both yield and sequence selectivity of a template-controlled PNA-ligation. The highest selectivity was obtained with a peptide condensation that formed an abasic site.

Graphical abstract: Sequence fidelity of a template-directed PNA-ligation reaction

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Article information


Submitted
10 Jul 2001
Accepted
29 Aug 2001
First published
14 Sep 2001

Chem. Commun., 2001, 2050-2051
Article type
Communication

Sequence fidelity of a template-directed PNA-ligation reaction

A. Mattes and O. Seitz, Chem. Commun., 2001, 2050 DOI: 10.1039/B106109G

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