Conformation of chiral alkoxyallenes by proton NMR spectroscopy
Abstract
A comparison of steady-state NOE coefficients measured for 3-O-allenyl-substituted furanoses in [2H8]toluene solution with conformations generated by a molecular mechanics program allowed characterisation of the most favourable ground state conformations. The geometry assigned from NOE coefficients corresponds well to that obtained by X-ray structure analysis of allene 1.