Regioselective SN2 opening of α,β-ethylenic epoxides by RLi–BF3 combination
Abstract
Organolithium reagents effect a regioselective SN2 nucleophilic cleavage of α,β-ethylenic epoxides only when BF3·Et2O is added. The reaction works with a variety of RLi reagents and with cyclic as well as acyclic