Issue 10, 2000

Bite angle effect of bidentate P–N ligands in palladium catalysed allylic alkylation

Abstract

Two series of new bidentate P–N ligands have been synthesized. Application of these ligands in the palladium catalysed allylic alkylation of crotyl chloride and cinnamyl chloride leads to the preferential formation of the branched product. A larger bite angle of the ligand leads to higher regioselectivity. Stoichiometric alkylation of the complex [Pd(C4H7){p-MeOC6H4C[double bond, length half m-dash]N(CH2)4OPPh2}][O3SCF3] proceeds with 88% regioselectivity to the branched product.

Supplementary files

Article information

Article type
Paper
Submitted
18 Feb 2000
Accepted
28 Mar 2000
First published
28 Apr 2000

J. Chem. Soc., Dalton Trans., 2000, 1549-1554

Bite angle effect of bidentate P–N ligands in palladium catalysed allylic alkylation

R. J. van Haaren, C. J. M. Druijven, G. P. F. van Strijdonck, H. Oevering, J. N. H. Reek, P. C. J. Kamer and P. W. N. M. van Leeuwen, J. Chem. Soc., Dalton Trans., 2000, 1549 DOI: 10.1039/B001355M

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