Issue 23, 2000

Synthesis of substituted α-methylene-γ-butyrolactones from chloroformates via palladium catalysed cyclisation–anion capture

Abstract

Cyclisation of chloroformates onto proximate alkyne functionality in the presence of a Pd(0) catalyst followed by anion capture affords α-methylene-γ-butyrolactone derivatives in moderate to good yields.

Article information

Article type
Communication
Submitted
17 Aug 2000
Accepted
05 Oct 2000
First published
21 Nov 2000

Chem. Commun., 2000, 2381-2382

Synthesis of substituted α-methylene-γ-butyrolactones from chloroformates via palladium catalysed cyclisation–anion capture

R. Grigg and V. Savic, Chem. Commun., 2000, 2381 DOI: 10.1039/B006842J

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