First totally diastereoselective opening of chiral triquinphosphoranes. A new access to enantiopure oxazaphospholidinesElectronic supplementary information (ESI) available: experimental procedures and characterization of compounds 6a–e, 7a–e, 8. See http://www.rsc.org/suppdata/cc/b0/b005884j/
Abstract
Asymmetric addition of isocyanate compounds on chiral triquinphosphoranes, tricyclic hydridophosphoranes, led by a total diastereoselective opening of the diazaphospholidine ring. This provides chiral bicyclic oxazaphospholidines in which an eight-membered ring is fused to the oxazaphospholidine ring by the P–N bond.