A ten-step enantioselective synthesis of an F ring lactone for CTX antibody assay development, employing vitamin C as a starting material, is described.
The vitamin C route to the ciguatoxins: enantioselective synthesis of a ring F building block
S. Bond and P. Perlmutter, Chem. Commun., 2000, 567 DOI: 10.1039/A910163M
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